With his election to the New York State Senate in 1910, Franklin D. Roosevelt sets out to make a name for himself in Albany, much as Theodore Roosevelt had done twenty-nine years earlier. He joins forces with reform-minded Democrats to fight against the powerful bosses of their own party, and battles for state government and labor reforms – but to the dismay of many, his support is sometimes unreliable. For Eleanor Roosevelt, distance away from her mother-in-law enables her to thrive in this new atmosphere of politics and public service. Then on February 24, 1912, Theodore Roosevelt, restless and disappointed with his handpicked successor to the White House, announces his candidacy for president. The 1912 fight for the Republican nomination between Theodore Roosevelt and William Howard Taft is brutal, and TR's supporters form their own third party, the Progressive "Bull Moose" Party. TR will survive an assassination attempt and go on to defeat Taft in the general election, but by splitting the ticket, he ensures the election of Democrat Woodrow Wilson as President. Franklin Roosevelt's campaign for re-election to the State Senate is hampered by a bout of typhoid fever, but with the help of Albany newspaperman, Louis Howe, he easily wins re-election. Not long after, FDR happily accepts President Wilson's appointment as Assistant Secretary of the Navy, and moves his family to Washington, DC. Devastated by his humiliating defeat in 1912, Theodore Roosevelt and his son, Kermit, set off to explore a rapids-choked, unmapped tributary of the Amazon River, the River of Doubt. The men encounter danger, illness and accidents, and TR nearly dies. When the explorers emerge two months later, Theodore Roosevelt is fifty-five pounds lighter and suffering from illnesses that will affect his health for the rest of his life. Germany declares war in August 1914, and by the end of the year almost all of Europe and part of Asia are engulfed in the conflict. President Wilson's unyielding neutrality prompts open anger in Theodore Roosevelt, with his cousin, Franklin, quietly agreeing with the former president's position. When TR finds himself on trial for libel against a New York Democratic boss, his "nephew by law, " Franklin, willingly testifies on his behalf. Meanwhile, Sara Roosevelt has her Hyde Park home remodeled to accommodate Franklin and Eleanor's growing family. It is a sanctuary for the children but with FDR mostly away in Washington, Eleanor is often left alone to negotiate life with her interfering mother-in-law and five active children. Woodrow Wilson is re-elected by a small margin and continues to maintain American neutrality well into 1917. Once war is declared on April 2nd, both Theodore and Franklin seek approval to serve in the military, but both are refused. For Eleanor Roosevelt, the war becomes her stepping-stone to freedom and the means to develop the skills and sensitivity to others that in the future will push her to "…do what you think you cannot." Theodore Roosevelt's disappointment in being denied a place in the Great War does not stop him from encouraging all four of his sons to enlist. But when the youngest, Quentin, is shot down over France in the summer of 1918, TR is devastated. In July 1918, Franklin Roosevelt persuades his boss to allow him to inspect the troops in Europe. FDR delights in the experience, but sails home two months later with double pneumonia. Upon his return, Eleanor discovers a bundle of love letters between Franklin and her one-time personal secretary, Lucy Mercer. She offers Franklin his "freedom." But when his mother warns that she will withdraw financial support, and Louis Howe lets him know this will end his political career, FDR promises never to see Lucy Mercer again. The Great War ends on November 11, 1918. Theodore Roosevelt, grieving over his son's death and in poor health, still has hopes of seeking the presidential nomination in 1920. But on the night of January 5, 1919, the former president goes to bed at his beloved Sagamore Hill and never wakes up. He is just sixty years old.